Question 1

Does KPV cause skin tanning or pigment changes?

Accepted Answer

No. KPV is the C-terminal tripeptide of alpha-MSH and completely lacks the central His-Phe-Arg-Trp core sequence required to activate MC1R-mediated melanin synthesis.

Question 2

How does KPV target inflamed areas specifically?

Accepted Answer

Inflamed tissues heavily upregulate the PepT1 transporter. KPV uses PepT1 to selectively enter inflamed epithelial cells and immune cells in high concentrations.

Question 3

What is the molecular formula and CAS number?

Accepted Answer

Molecular Formula: C16H31N5O4, Molecular Weight: 357.45 g/mol, CAS Number: 67727-97-3.

Question 4

How should KPV be reconstituted and stored?

Accepted Answer

Reconstitute with sterile Bacteriostatic Water or sterile 0.9% saline. Store lyophilized vials at -20°C. Reconstituted solutions should be refrigerated at 2°C to 8°C.